A Study of Invasiveness and Toxicity of Cholera, Para-Cholera and Saprophytic Vibrios in Animals
نویسندگان
چکیده
Koch (1886) studied the effect of cholera vibrios on guinea-pigs by feeding the animals with big doses of the organisms and then paralysing the gut by intraperitoneal injection of 1 c.cm. of tincture of opium so as to delay evacuation. Out of 35 animals, 30 died showing weakness of the hind limbs and collapse. The small intestine was deeply injected and filled with a;flocculent colourless fluid which contained V. cholera; in almost pure culture. Thomas (1893) injected living vibrios intravenously into adult rabbits, and found ecchy-
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